The third volume in the Handbooks in Health Economic Evaluation series, this book provides the reader with a comprehensive set of instructions and examples of how to perform an economic evaluation of a health intervention. It focuses solely on cost-effectiveness analysis in health care. The book is developed out of the Advanced Methods of Cost-Effectiveness Analysis course taught at the University of Oxford and the four main sections mirror the four principal components of thecourse: Outcomes, Costs, Modelling using decision tress and Markov models, and Presenting cost-effectiveness results.&L