London, 1853. Annie Stride is a beautiful, flame-haired young woman from the East End of London. She is also a whore. On a bleak January night Annie stands on Waterloo Bridge, watching the icy waters of the Thames writhe beneath her as she contemplates throwing herself in. At the last minute she's rescued by a handsome young man. Her saviour, Francis Maybrick Gill, is a talented artist. He takes Annie as his muse, painting her again and again and transforming her from a fallen woman into society's darling, taking her far away from her old life. But there is darkness underpinning Annie's lavish new lifestyle. In London and in Florence, prostitutes are being murdered. There's someone out there who knows who Annie really is - and they won't let her forget where she came from...