SSDBM 2006 explores original research contributions and practical system design, implementation and evaluation. The conference brings together scientific domain experts, database researchers, practitioners and developers for the presentation and exchange of current research on concepts, tools and techniques for scientific and statistical database applications. SSDBM explores scientific database management, experiment data management, data streams and time series data, data mining and visualization, conceptual modeling and OLAP, ontologies and metadata management as well as algorithmic aspects of scientific data.