This volume is based on the proceedings of the International Symposium on "Strangeness in Nuclear and Hadronic Systems (SENDAI08)", which is the third in a series of symposia on nuclear physics involving strangeness following SENDAI98 and SENDAI03. With the expectation of the completion of new accelerator facilities such as J-PARC and other new experimental facilities, recent theoretical and experimental results and future prospects of strangeness nuclear physics are discussed in great depth by leading experts of the field. The topics involved are electromagnetic production of strangeness, structure and decay of hypernuclei, hyperon-nucleon and hyperon-hyperon interactions, among others. It will also serve as a good textbook for studying the current status of strangeness in nuclear and hadronic physics.