To improve survival and quality of life among the 2.5 million children living with HIV a comprehensive package of prevention care and treatment is required. This package should include management of infections such as pneumonia diarrhoea malaria and ear infections as well as common opportunistic infections and HIV-related co-morbidities. WHO is developing a series of guidelines on each of these conditions following the GRADE approach. The document on the management of pneumonia and diarrhoea in HIV-infected infants and children is the first of this series. The recommendations are similar to th