The moon of LV-223-resting place of the doomed Prometheus expedition, enigmatic source of all organic life, and nightmarish source of ultimate destruction. 126 years later, a new generation of explorers hope to uncover the mysteries of this strange and dangerous world, but what they find includes not just the ruins of the Prometheus mission, but also the alien horrors of what was found at Hadley's Hope on LV-426, and an encounter with an interstellar race of hunters - all of which may lead to humanity's undoing.