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The Code Breaker: Jennifer Doudna, Gene…
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The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race (2021. Auflage)

von Walter Isaacson (Autor)

MitgliederRezensionenBeliebtheitDurchschnittliche BewertungDiskussionen
1,2605015,175 (4.19)88
Biography & Autobiography. Science. Nonfiction. HTML:A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a "compelling" (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn't become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book's author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm...Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an "enthralling detective story" (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.
… (mehr)
Mitglied:streamsong
Titel:The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race
Autoren:Walter Isaacson (Autor)
Info:Simon & Schuster (2021), Edition: First Edition, 560 pages
Sammlungen:Deine Bibliothek, Gelesen, aber nicht im Besitz, Library book, Read in 2021
Bewertung:*****
Tags:non-fiction, biography, biology, CRISPR, genetics, history of science, Jennifer Doudna, science, gene-editing, scientific ethics

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The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race von Walter Isaacson

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I thought this would be more of a biography of Jennifer Doudna then it was, but still enjoyed it. Kind of an overview of crispr, the various scientists that were involved in its discovery and what it all means. along the way you get an inside look at how research science works, how patents and corporate culture are effecting academia and also the nobility of curiosity for its own sake ( )
  cspiwak | Mar 6, 2024 |
A great, timely, and important book. Timely, strategic issues (genetic editing...) discussed.
Very readable, as I have found all of Isaacson's books, though this one is especially heavy with acronyms.
It sometimes felt like a combo of Agatha Christie and Sherlock Holmes. ( )
  jjbinkc | Aug 27, 2023 |
Great on history, too much philosophy

When focusing on the biography and storytelling, the history of Doudna and CRISPR, it’s phenomenal. When Isaacson drones in about the philosophy of gene editing, it’s almost a chore to read.
( )
  RyneAndal | Jul 12, 2023 |
It was truly enlightening, getting to discover CRISPR. @ some point i felt like the author veered a little off course with all the stories about Doudna and the double helix guy, the one spewing racist BS.
I'm really looking forward to hear more about the effective use of CRISPR in the fight against Covid cause these vaccines seem like a temporary fix. ( )
  NG_YbL | Jul 12, 2023 |
Book on CD read by Kathe Mazur and Walter Isaacson

Subtitle: Jennifer Doudna, Gene Editing, and the Future of the Human Race

This is an engaging, interesting, informative, and thought-provoking biography cum history. While the focus is on Jennifer Doudna, Isaacson gives almost equal time to the many other researchers who contributed to the scientific discoveries and applications.

The book starts out with basic biographical background, moves into the excitement of discovery and the international race to obtain patents, and to publish first, then on to ethical questions surrounding the application of new technologies, and finally focuses on the ways that these teams of scientists worked to address COVID19.

Isaacson frequently puts himself into the narrative, writing in first person about his encounters and reactions.

The audiobook is narrated by Kathe Mazur, with an introduction and epilogue narrated by Isaacson. I was happy that I had the text handy because there are times when reading a passage helped me understand the science better than listening to it. But Mazur is a very talented voice artist, and she really did a magnificent job. ( )
1 abstimmen BookConcierge | Apr 9, 2023 |
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AutorennameRolleArt des AutorsWerk?Status
Walter IsaacsonHauptautoralle Ausgabenberechnet
Mazur, KatheErzählerCo-Autoreinige Ausgabenbestätigt

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Biography & Autobiography. Science. Nonfiction. HTML:A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a "compelling" (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn't become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book's author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm...Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an "enthralling detective story" (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.

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