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The Code Breaker: Jennifer Doudna, Gene…
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The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the… (2021. Auflage)

von Walter Isaacson (Autore)

MitgliederRezensionenBeliebtheitDurchschnittliche BewertungDiskussionen
5502734,476 (4.24)63
Titel:The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race
Autoren:Walter Isaacson (Autore)
Info:Simon & Schuster (2021), 536 pages
Sammlungen:Chicago Office Library


The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race von Walter Isaacson

Kürzlich hinzugefügt vonprivate Bibliothek, TonyDib, DalvignyHistory, warren5350, WaterBooks, greenefrog, sriram_shankar
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I was a bit daunted by the size of the book when I picked up "The Code Breaker" at my local library. I knew I had to start reading it right away when I checked my library site to find out there were many more holds waiting. That said, the short chapters and style of writing helped to speed the pages along.

The author told the story of the scientific discoveries relating to gene editing through the personalities involved. That led an interesting tale of rivalries and the monetization of scientific discoveries. In some cases, it read almost like a thriller. It was also a wonderful build up to show the contrast with the sharing philosophy scientists and governments adopted when there was a common emergency due to the Covid pandemic.
  Familyhistorian | Jan 16, 2022 |
this unforgettable work reveals how Nobel Prize winner Jennifer Doudna and her colleagues created CRISPR, a scientific advance that shook the world… and delves into the powerful implications of DNA editing.

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.
Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.
The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.
Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?
After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.
  Gmomaj | Jan 11, 2022 |
In 2012 Jennifer Doudna invented a way to edit DNA. Nobody knew then that 8 years later the world would be in a pandemic. Vaxers or Anti-Vaxers should at least know a little about the science of viruses and DNA, this well written and informative book can do that for you.
It's also an interesting look at how science is done today in the United States. ( )
  kevn57 | Dec 8, 2021 |
Although I mostly read fiction, I have been aware of Walter Isaacson and his portrayals of people like Einstein, and Steve Jobs among others. A friend in a book club is reading this so I thought I would give it a try. It is almost 500 pages and in parts very technical but ultimately the big picture of the book is an excellent portrayal of the people involved with the development of the gene editing tool CRISPR. This tool has opened up the world of gene editing and with the positive and negative as to how this tool can be used. It focuses around Jennifer Doudna but it brings many people involved in biotech and with the history of discoveries in DNA etc. Isaacson humanizes the characters is this drama. It does get technical but for me it give me an overview that I didn't have. Also the development of the Pfizer and Moderna vaccines owe their breakthrough vaccine process to developments in gene editing. The books deals with ethical issues that we face as we begin to use gene editing as we try to eliminate diseases such as Huntingtons and Sickle Cell anemia. However was also have to deal with issue of enhancements and how that can effect natural selection as we move forward. As we have seen with all great inventions such as the computer, internet, etc. there is always the probability of bad actors entering into the field. Ultimately, the book does a great job of bringing up the big issues facing us as we become more proficient in being able to eliminate and enhance the human genes. Will it always be positive? ( )
  nivramkoorb | Dec 5, 2021 |
[Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race] by [[Walter Isaacson]]

This book seemed obviously rushed to press. Isaacson took a fascinating subject, the science behind gene editing using discoveries made while studying RNA, and makes the science secondary to a juvenile telling of the in-fighting between the scientists as they raced to publish their findings first. The human story becomes a string of short bios and the language was so simplistic that I checked several times to see if I'd mistakenly downloaded the youth version on my kindle.

This is too bad, because it's a fascinating topic, and Isaacson certainly could have included a focus on the scientists in addition to describing the science, but it just wasn't executed well. I would have been thrilled to read a good biography of a woman scientist, but even Jennifer Doudna, who gets a nod in the title, doesn't get a deep enough attention in the book to satisfy my curiosity.

I was hoping for a science book in the vein of [The Gene] by [[Siddhartha Mukherjee]] and this comes no where close. I felt this was rushed to publish because the science was used in creating the mRNA covid vaccines.

The book gets a lot of high ratings on LT and elsewhere, but I didn't see it.

Original publication date: 2021
Author’s nationality: American
Original language: English
Length: 552 pages
Rating: 2 stars
Format/where I acquired the book: library kindle book
Why I read this: interested in the topic ( )
  japaul22 | Nov 12, 2021 |
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To the memory of Alice Mayhew and Carolyn Reidy. What a joy it was to see them smile.
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Durchschnitt: (4.24)
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