South African Cosmologist George Ellis was awarded the Templeton prize for progress toward research or discoveries about spiritual realities. On his visit to London to receive the prize, he gave a talk about the interaction of science and religion, at an event organized by Quaker Quest at Friends House. This pamphlet is an edited version of the talk. Physics alone cannot account for intentional factors in everyday life, like why someone shaped these spectacles with their particular curvature. So how do theories of the universe relate to human ethics and values, to faith and hope?